Evolution of Insulin

Evolution of Insulin and How it Informs Therapy and Treatment Choices: This article reviews the history and evolution of insulin therapy, from animal extracts to synthetic human insulin and insulin analogs, and discusses the current challenges and opportunities for improving insulin treatment¹.

- An all-in-one approach to diabetes treatment: This article describes a new device developed by MIT engineers that can streamline the process of blood glucose measurement and insulin injection, by combining many of the existing steps into a single device.

- [Scientists discover a new promising target for diabetes treatment]: This article reports on a novel and druggable insulin inhibitory receptor, named inceptor, that can be blocked to increase the sensitisation of the insulin signaling pathway in pancreatic beta cells⁴.

- [New discovery could pave the way for improved treatments for diabetes]: This article reveals a pathway to the regeneration of insulin in pancreatic stem cells, discovered by Monash University researchers, which could lead to new therapies to treat Type 1 and Type 2 diabetes.

- [Diabetes: Experimental drug may help restore insulin production]: This article explains how a drug previously used for treating lymphomas and multiple myeloma can reactivate the genes that regulate insulin expression, suggesting a possible new treatment option for diabetes patients who rely on daily insulin injections.