DOXIUM 30 capsules - 500 mg.

Features / mode of action

Calcium dobesilate acts on the capillary walls damaged by regulating their physiological functions: increased throughput and reduced resistance. It increases the flexibility of red blood cells, inhibits enhanced platelet aggregation, and diabetic retinopathy (a complication of diabetes, including damage to the vessels of the eye) reduces elevated plasma and blood viscosity, thereby improving the properties of blood and tissue blood flow. These properties allow calcium dobesilate to correct capillary failure caused by functional deficiency or congenital or acquired metabolic disorders. Calcium dobesilate helps reduce swelling.

Witness

Microangiopathy (damage to the blood vessels with low flow), especially diabetic retinopatiya.Pokazan clinical manifestations of chronic venous insufficiency of the lower limbs (pain, cramps, paresthesia / impaired sensitivity, edema, stasis, dermatitis). Apply and concomitant treatment superficial thrombophlebitis (superficial blood vessel blockage).

For the treatment of hemorrhoidal syndrome microcirculatory disorders arteriovenous origin.

Dosage and method of administration

The usual dose is 500-1000 mg - 1 capsule once or twice daily, during hranene.Prodalzhitelnostta treatment depends on the disease and its development from a few weeks to several months

Dosage should be individually adjusted to the severity of the disease.

Restrictions on use

Contraindications

Hypersensitivity to calcium dobesilate or any of the excipients of produkta.Spetsialni warnings and precautions for use. In case of severe renal failure requiring dialysis, the dose should be reduced.

In very rare cases (0.32 / 1,000,000 people), the intake of calcium dobesilate can cause agranulocytosis (lack of certain types of cells from white blood cells), probably associated with a hypersensitivity reaction. This condition may occur with symptoms such as fever, oral infections, sore throat (tonsillitis), inflammation of the area around the anus and genitals, with accompanying symptoms are often signs of infection. The patient should immediately inform your doctor of these symptoms. In such cases must be initiated blood counts (levkograma), and the treatment is stopped.

Pregnancy and lactation

Pregnancy Category C.

No studies on the effects of calcium dobesilate in pregnant animals or women. Since it is not known whether calcium dobesilate cross the placental barrier in humans is used if it is determined that the benefits exceed its possible risk to the fetus. Calcium dobesilate passes into breast milk in very small quantities (0,4 pg / ml after administration of 3 x 500 mg). As a precaution should be discontinued or breastfeeding, or treatment.

Effects on ability to drive and use machines

DOXIUM  500 has no effect on ability to drive and use machines.

Adverse reactions

Rare: gastrointestinal disturbances, including nausea and diarrhea, rashes and vtrisane.Pri gastrointestinal complaints, the dosage is reduced or treatment temporarily prekratyava.Pri skin reactions and fever, treatment should be discontinued and the patient should inform the doctor immediately because you may have an allergic reaction.

In long-term skin reactions and respiratory problems, treatment should be discontinued, as these events can have allergic reactions.

Drug Interactions

These are not known.

Overdose

Signs of overdose has been reported.

Incompatibilities

There are currently unknown.

Expiration dat 

Store in original containers, DOXIUM  500 has a shelf life of 5 years.

Special precautions for storage

The product should be stored in a dry place at room temperatura.Da not use after the expiration date printed on the package, along with the clarification "EXP."

Of container.

Carton containing 30 capsules.

INGREDIENTS:
 
Active substance: 1 capsule contains 500 mg calcium dobesilate (calcium dobezilat).
 
Excipients: magnesium stearate, maize starch.